余祥(博士),教授(高聘),湖北省楚天学者,第十届中国免疫学会“青年学者奖”获得者。2013年毕业于武汉科技大学医学院临床医学专业,获医学学士学位;2019年毕业于华中科技大学武汉光电国家研究中心生物医学工程专业,获工学博士学位,同年就职于三峡大学医学院(校聘副教授),2021年获评三峡大学“优秀教师”,以第一指导老师指导本科生获得国家级和省级奖励各4项,市级和校级各1项;2023年2月入职海南大学生物医学工程学院,加入免疫调控与成像团队(负责人张智红教授)。
主要研究方向:
1)慢性疾病的免疫调节与多模态成像可视化
2) 区域免疫器官互作研究
近5年学术论文:
1) Xiang Yu1, Yanfeng Dai1, Yifan Zhao, Shuhong Qi Lisen Lu, Qingming Luo, Zhihong Zhang*. Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response. Nature Communications, 2020, 11(1), 1-14.
2) Xiang Yu, Lu Chen, Jianqiao Liu, Bolei Dai, Guoqiang Xu, Guanxin Shen, Qingming Luo*, Zhihong Zhang*. Immune Modulation of Liver Sinusoidal Endothelial Cells by Melittin Nanoparticles Suppresses Liver Metastasis. Nature Communications, 2019, 10(1): 574.
3) Yanfeng Dai1, Xiang Yu1, Jianshuang Wei1, Fanxin Zeng, Yiran Li, Xiaoquan Yang, Qingming Luo*, Zhihong Zhang*. Metastatic status of sentinel lymph nodes in breast cancer determined with photoacoustic microscopy via dual-targeting nanoparticles. Light: Science & Applications. 2020, 9: 164.
4) Ni Yang, Miaomiao Li, Ling Wu, Yinhong Song, Shi Yu, Yingying Wan, Wenjing Cheng, Baoye Yang, Xiaoqin Mou, Hong Yu, Jing Zheng, Xinzhi Li*, and Xiang Yu*. Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis. Journal of Nanobiotechnology, 2023, 21(1): 1-20.
5) Xiang Yu1*, Siyu Jia1, Shi Yu1, Yaohui Chen, Chengwei Zhang, Haidan Chen* , Yanfeng Dai*. Recent advances in melittin-based nanoparticles for antitumor treatment: from mechanisms to targeted delivery strategies. Journal of Nanobiotechnology, 2023, 21(1): 454.
6) Wenjing Cheng, Xiangbai Wu, Shi Yu, Chengwei Zhang, Yinhong Song, Xinzhi Li, Xiang Yu*. Biomimetic nanoplatform with selectively positioned indocyanine green for accurate sentinel lymph node imaging. Nanoscale, 2023, 15(47): 19168-19179.
7) Gan Zhang, Wenjing Cheng, Ni Yang, Baoye Yang, Shi Yu, Jing Zheng, Miaomiao Li, Yaling Fu, Xinzhi Li, Yinhong Song, Zhihong Zhang*, Xiang Yu*. Peptide-decorated Artificial Erythrocyte Microvesicles Endowed with Lymph Node Targeting Function for Drug Delivery. Advanced Therapeutics, 2023: 2200236.
8) Jing Zheng, Ni Yang, Yingying Wan, Wenjing Cheng, Gan Zhang, Shi Yu, Baoye Yang, Xinyu Liu, Xingyan Chen, Xueliang Ding, Ling Wu*, Xiang Yu*. Celastrol-loaded Biomimetic Nanodrug Ameliorates APAP-induced Liver Injury through Modulating Macrophage Polarization. Journal of Molecular Medicine, 2023, 101(6): 699-716.
9) 杨梓萌, 程文静, 余祥*. 新型纳米递送系统在药物诱导肿瘤细胞焦亡中的应用.中国肿瘤生物治疗杂志, 2022.(专家论坛)
10) Baoye Yang, Decheng Wang, Shi Yu, Chengwei Zhang, Jing Ai, Xiang Yu*. Breaking CHIPS-Mediated immune evasion with tripterin to promote neutrophil chemotaxis against MRSA infection. International Immunopharmacology, 2024, 129: 111597.
11) Shiqi Luo, Xinghua Meng, Jing Ai, Zhihong Zhang, Yanfeng Dai*, Xiang Yu*. Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice. International Journal of Molecular Sciences, 2024, 25(6): 3411.
12) Jing Zheng, Qiulin Yuan, Cao Zhou, Weifeng Huang, Xiang Yu*. Mitochondrial stress response in drug-induced liver injury. Molecular Biology Reports, 2021.48(10), 6949-6958.
主持科研项目:
1) 国家自然科学基金面上项目,2025/01-2028/12,在研,主持。
2) 国家自然科学基金青年科学基金项目,2022/01-2024/12,在研,主持。
3) 湖北省自然科学基金(面上项目),2020/03-2022/03,结题,主持。
4) 肿瘤微环境与免疫治疗湖北省重点实验室开放基金,2023/09-2025/09,在研,主持。
5) 湖北省胃肠癌精准防治临床医学研究中心开放基金,2022/09-2024/09,结题,主持。
招生需求:
招收生物信息学、免疫学、生物医学工程、药学及医学检验等相关专业研究生
联系方式:yuxiang@hainanu.edu.cn