姓 名:尹凯
职 称:高聘副研究员
导师类别:硕士生导师
E-mail:996523@hainanu.edu.cn
一、个人基本情况
尹凯,男,博士,高聘副研究员,硕士生导师,海南大学高层次引进人才
二、教育工作情况
2012.9-2017.6 东北农业大学 动物医学专业 农学学士
2017.9-2020.6 东北农业大学 临床兽医学专业 农学硕士
2020.9-2023.6 东北林业大学 林学专业 农学博士
2023.09-至今 海南大学生命科学学院 高聘副研究员
三、科研情况
从事环境污染物对生物体的毒理学机制研究,主要研究微塑料暴露对生物体消化系统毒性及免疫毒性。
四、研究领域
环境污染物的毒理学机制研究。
五、代表性成果
第一作者成果
(1) The antagonistic effect of Se on the Pb-weakening formation of neutrophil extracellular traps in chicken neutrophils. Ecotoxicology and Environmental Safety (2019). IF:7.129, Q1,中科院二区,TOP 期刊。
(2) Hydrogen sulfide upregulates miR-16-5p targeting PiK3R1 and RAF1 to inhibit neutrophil extracellular trap formation in chickens. Ecotoxicology and Environmental Safety (2020). IF:7.129,Q1,中科院二区,TOP 期刊。
(3) Antagonistic effect of selenium on lead-induced neutrophil apoptosis in chickens via miR-16-5p targeting of PiK3R1 and IGF1R. Chemosphere (2020). IF:8.943, Q1,中科院 二区,TOP 期刊。
(4) A comparative review of microplastics and nanoplastics: Toxicity hazards on digestive, reproductive and nervous system. Science of the Total Environment (2021). IF:10.753, Q1,中科院一区,TOP 期刊,ESI 高被引。
(5) Microplastics pollution and risk assessment in water bodies of two nature reserves in Jilin Province: Correlation analysis with the degree of human activity. Science of the Total Environment (2021). IF:10.753,Q1,中科院一区,TOP 期刊。
(6) Polystyrene microplastics up-regulates liver glutamine and glutamate synthesis and promotes autophagy-dependent ferroptosis and apoptosis in the cerebellum through the liver-brain axis. Environmental Pollution (2022). IF:9.988,Q1,中科院二区,TOP 期刊,ESI 高被引。
(7) Secondary brain injury after polystyrene microplastic-induced intracerebral hemorrhage is associated with inflammation and pyroptosis. Chemico-Biological Interactions (2022). IF:5.168,Q1,中科院二区。
(8) Dose-effect of polystyrene microplastics on digestive toxicity in chickens (Gallus gallus): Multi-omics reveals critical role of gut-liver axis. Journal of Advanced Research (2022). IF:12.822,Q1,中科院二区。
(9) Polystyrene microplastics promote liver inflammation by inducing the formation of macrophages extracellular traps. Journal of Hazardous Materials (2023). IF:14.224, Q1,中科院一区,TOP 期刊。